| W:
|
Indicates one of the 312 drugs (at December 1999)
included in "the eleventh model list of essential drugs" issued by WHO
(world Health Organization) (translated by Hama and Beppu, Sanseido 2000).
Most of medical practices except rare diseases) could be done by these
drugs even in Japan. The drugs included in the list was expressed as w
○›. If the drug were approved in UK, US, Canada,
Australia, expressed as UK○,US○, CA○, AU○.
Classification of NPOJIP: classified by NPOJIP
originally.
|
| AA:
|
Absolutely necessary for many
patients and no other drug is available as alternatives.
As it is a drug, misuse may cause adverse effects,
but it may be relatively safe so far as it is used properly. Caution is
necessary to avoid adverse reactions.
|
| A:
|
Absolutely necessary for many
patients.
Although other drugs are available as
alternatives, this is the choice among the same class of drugs. As proper
use of the drug could induce adverse reactions, it should be used
considering the risk/benefit ratio always. It is inevitable for you to use
it after knowing the information of adverse effects.
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| AK:
|
Absolutely
necessary for medical practices, but special caution
is necessary as it induce adverse reactions frequently
as it is used improperly frequently and even if it is
used properly.
You should use this drug after you
are very familiar with adverse effects of this drug.
K means "KIKEN" (danger in Japanese) or sometimes
means "KILL".
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| B:
|
Necessary for many
patients.
Many drugs are available as alternatives and this
is not the first choice among the same class of drugs. As proper use of
the drug could induce adverse reactions, it should be used considering the
risk/benefit ratio always. It is inevitable for you to use it after
knowing the information of adverse effects, especially you have another
diseases and you are using other drugs.
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| C:
|
Restricted use
It is necessary occasionally but for very
restricted patients.
An abbreviation "K" may be added to B or C. The
drug ranked in BK or CK may induce serious adverse reactions by proper use
of the drug. It should be used especially cautiously considering the real
risk/benefit ratio always.
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| D:
|
Do not use it until more
information available.
New drugs and there is no proper evidence of
long-term efficacy and safety.
So it is recommended not to use it until more
evidence of true efficacy and safety would be available.
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| X:
|
Do not use.
Other drug is available for alternatives. It is not
necessary.
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| XK:
|
Never use it!!
Not only lacking evidence of efficacy especially
for long term use but also there are substantial evidence indicating
definite or almost definite bad effects and thus it should never be used
|