CHECK-UP YOUR MEDICINE
TO SAVE YOUR LIFE
"Kusuri-no-check-wa-inochi-no check"
Published by NPOJIP

Contents of the First issue of the new Bulletin are as follows　　　　translated article(##)

Contents

1.

Preface for the first issue

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2.

What is NPOJIP?

3.

Message from abroad------DR. Andrew Herxheimer

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4.

Very important things for the management of Diabetes mellitus

5.

Good nutrients and foods for diabetes mellitus are good for everybody

6.

Principles of treatment of diabetes mellitus

7.

Classification of value of pills

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8.

Principles of drugs for diabetes mellitus

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9.

Leaflets of drugs for patients

1）Insulin
2）Sulfonylureas
3）Metformine
4）Alpha-glycosidase inhibitors
5）Epalrestat (aldose reductase inhibitor)
6）Pioglitazone

excellent(ESSENTIAL)
not so important as insulin
not so important as insulin
not so important as insulin
should be withdrawn
should be withdrawn

10.

Don't use Kinedac(epalrestat=aldose ceductase inhibitor)!!
　　　No proof of efficacy and potential liver toxicity

11.

Don't use Actos(pioglitazone)!!
No proof of long-term efficacy and highly potential heart toxicity
Risk is estimated far higher than benefit in long term use

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12.

Words heard at hospitals

1)Diabetes mellitus 　poor meal is also harmful for blood vessels

2)Nutrients 　three mejor nutrients should be balanced in every meal

3)Blood glucose level, hypoglycemia(low blood glucose level) and hyperglycemia(high blood glucose level 　　hypoglycemia is more dangerous than hyperglycemia

4)Urinalysis 　　valuable for screening many diseases including DM

5)Glucose tolerance test 　　inevitable for accurate diagnosis of DM

7)HbA1c 　　　reflecting past one-month glucose level

6)Insulin 　　　far more valuable than glucose lowering pills

8)Heart failure 　　difficult to breath as heart cannot work well

9)Influenza 　　　the most epidemic is type A

10)Principles how to prevent and how to treat flu (influenza)　　vaccines is not effective for prevention and proper rest for treatment

11)Vaccines 　　protect to get ill, only immunization

12)Adverse effect of vaccine risk become larger than benefit as incidence of the disease decreases

13)Immunization 　　protect body from foreign bodies(pathogens etc)

14)Common cold 　　antibiotics and antipyretics are unnecessary

15)Inflammation 　　repair the damaged part of the body

16)Antipyretics 　　　occasionally worsen the diseases

13.

How to communicate doctors 　　case study

1)pharmacist and doctor: a trial by a pharmacist to recommend a doctor to stop Actos in treating a patient who experienced edema during the use of Actos.

2)Patient (family) and doctor: for better terminal palliative care

14.

Series

1)How to read animal toxicity study.
　Is there any fault in animal test?
　(Presenting the animal toxicity test in pioglitazone case)

2)Relay essay: 　experiencing being diagnosed as DM

3)Report from Washington DC by Yoshiko: collaborating Public Citizen

4)Bioethics in lay language

15.

Topic 1.

Will flu-vaccine-shortness-pathy prevail also in this winter?
Criticizing the campaign of mass-media claiming shortness of influenza-vaccine that is without evidence of efficacy and with many evedence of non-efficacy by our analysis.

Topic 2.

Don't use NSAIDs antipyretic. If you use any antipyretic, prefer paracetamol.
One step advance in the restrictionh of NSAIDs use, as correlation with encephalopathy was shown.

Topic 3.

Don't use decongestant!
Risk of brain hemorrhage, other stroke and heart attack, and arterial infarction for the decongestants containing sympathetic nerve stimulants including PPA

16.

Editorial

Continuing epidemic of encephalopathy related to the continuing use of NSAIDs as antipyretic is a drug disaster comparable with SMON and blood-products-induced HIV.

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17.

Guidance of publications by NPOJIP and others

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